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VWD Classification	Nucleotide Change	Amino Acid Substitution	Functional Studies	Country	Laboratory	Comments
Type 2B	4022G>A	R1341Q	No
Type 2B	4022G>A	R1341Q	Yes
Type 2B	4022G>A	R1341Q	No		Sixma, Mazurier
Type 2B	4022G>A	R1341Q	No
Type 2B	4022G>A	R1341Q	No		Ginsburg
Type 2B	4022G>A	R1341Q	No	Canada	Lillicrap
Type 2B	4022G>A	R1341Q	?